|Previous portrait||Dr. Cassandra Fraser
College & Graduate School of Arts & Sciences
Research in the Fraser Lab is concerned with the synthesis, properties and applications of metal complexes with polymeric ligands. Like metalloproteins, polymeric metal complexes feature site-isolated metal centers in well-defined macromolecular environments. These multifunctional targets are prepared via combination of coordination chemistry with living polymerization methodologies and offer many opportunities for further modification. The development of new synthetic methodologies has paved the way for the discovery of some fascinating and unexpected properties and reactivity. The resulting hybrid materials can function as soluble agents, films, nanoparticles, or bulk materials, and block copolymers can form higher order nanoscale assemblies. Presently, we are exploring uses for these metallobiomaterials as optical imaging agents, oxygen sensors, drug delivery systems, and responsive materials in biomedicine and sustainable design.
Learn how the Fraser Lab is using metallobiomaterials in imaging and sensing applications for tumors, vascular blockage relevant to strokes and heart disease, organ transplantation, and other medical contexts.
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